Principal Investigator
José Pablo Vázquez-Medina
I am a broadly trained biologist with a strong interest in redox physiology. I have led research projects investigating the role of redox biology in adaptation and disease in a variety of systems, from humans to invertebrates, rodent models of diabetes, hypertension, and lung disease, and marine vertebrates.
Postdocs
Diana Daniela Moreno-Santillan
Postdoctoral researcher
I am an evolutionary biologist from Mexico City, where I obtained my BS in Biology from Universidad Nacional Autonoma de Mexico (UNAM). During my MS and PhD programs at the Instituto Politecnico Nacional, I developed an interest in evolutionary biology. My research focuses on the dynamics of aging and immunity from an evolutionary perspective, using comparative and integrative studies in mammals. For this, I have been performing comparative analysis at genomic and transcriptomic levels in mammals, with bats being my main species of interest. In the Vazquez-Medina lab, I am conducting comparative genomic analyses to understand diving adaptations in pinnipeds.
Dianna Xing
Postdoctoral researcher
I received my BA in Economics and Biological Chemistry from Grinnell College. Afterwards, I earned my PhD in the Biomedical Sciences from The University of Alabama at Birmingham under the guidance of Dr. Victor Darley-Usmar. I studied the effects of mitochondrial metabolites and redox signaling molecules on regulating cancer metabolism and bioenergetics in a hypoxia-reoxygenation model. Now at UC Berkeley with the Vázquez-Medina lab, I am interested in understanding the role of Peroxiredoxin-6 in regulating mitochondrial responses to oxidative stress using novel transgenic mice models.
Justin Lawrence Conner
Postdoctoral Researcher
I am a broadly trained comparative biologist originally from Miami, Florida. I received my undergraduate degree from Oregon State University, where I studied Zoology. During my PhD at the University of North Texas, I studied the physiology of ectotherms (American alligators, Burmese pythons, common snapping turtles, and air-breathing fish). After receiving an NSF Postdoctoral Fellowship to work at the University of Nevada Las Vegas, I developed the skills to create complex in vitro systems (organoids) in hibernating mammals. Recently, I joined the Vázquez-Medina lab supported by an NIGMS Diversity Supplement. Now, I am interested in studying the role of Prdx6 in regulating oxidative stress in renal dysfunction and acute kidney injury utilizing novel transgenic mouse models and cell culture systems.
PhD Students
B. Gabriela Arango
UC Berkeley Chancellor’s Fellow
Ford Predoctoral and Dissertation Fellow
I was born in Guadalajara, Mexico, and my academic journey began at Santa Rosa Junior College. I then pursued my BS and MS degrees in Biology at Sonoma State University. My master's research focused on the blood oxygen stores in olive ridley sea turtles, a remarkable physiological adaptation for breath-hold diving. Currently, I am investigating the evolutionary adaptations of sea turtles to withstand oxidative stress from extreme life stressors such as reproduction and hypoxic exposure during diving. I am passionate about science communication, engaging broad audiences of all ages in both formal and informal settings. In my free time, I love to play with Goku, the silliest German Shepherd.
Elizabeth Piotrowski
Berkeley Fellow
DOD NDSEG Fellow
I received my BS in Marine Biology from the University of Maine, Orono, where I conducted research in Kristina Cammen’s lab focused on developing new protocols that use environmental DNA for marine mammal studies. I then completed my MS in Biology at the University of the Pacific in Jane Khudyakov's lab, where I profiled muscle and blood gene expression related to carbon monoxide signaling and production across ontogeny and examined muscle and blubber transcriptome and proteome responses to swimming and diving in northern elephant seals. I'm interested in exploring adaptive mechanisms that protect diving mammals from hypoxia-induced oxidative stress and regulate energy balance. I enjoy volunteering at The Marine Mammal Center and hiking in my spare time.
Undergraduate Student Researchers
Malavika Garimella (Mala)
I am currently a sophomore studying Molecular and Cell Biology and Business Administration. I work with Kaitlin Allen in a project to understand and characterize adipose-derived stem cells isolated from the blubber of northern elephant seal pups during the post-weaning fasting period and develop a differentiation protocol for these stem cells. In my free time, I enjoy going out dancing, going cafe hopping and learning new languages.
Seoyun (Matthew) Lee
I am a freshman majoring in Molecular and Cell Biology (with emphasis on Molecular Therapeutics) and Economics. Under Dr. Dianna Xing's tutelage, I am studying the role of PRDX6 in the pathogenesis of diabetes and obesity using novel transgenic mice models. Outside of school, I enjoy traveling to different countries and incubating business ideas.
Kavi Singh
I am currently a third-year student at UC Berkeley majoring in molecular and cell biology, on the pre-med track. In the Vázquez-Medina lab, I am now working with Dr. Dianna Xing researching Peroxiredoxin-6, the effects of mutations in this enzyme, and its potential links to protecting mitochondrial function during metabolic disorders and inflammatory disease.
Affiliates
Juan Manuel Vazquez
NSF PRB Fellow, NIH K99 Postdoctoral Fellow, Sudmant Lab
I am a Puerto Rican scientist focused on evolution and longevity-associated traits in extraordinary animals. I study the within-species relationship between chromatin, gene expression, and aging in vivo using single-cell technologies in mice. Using functional genomics and primary cell culture in bats, whales, and elephants, I study the role of genomic stability and stress response in mediating between-species differences in lifespan.
Adi Domer
HFSP Fellow, Dudley Lab
I am an ecologist and a nature enthusiast from Israel. My fields of study include classical ecology and ecophysiology, particularly the evolutionary consequences of flight for animals' physiological traits. For this, I use a broad range of flying animals, including insects and birds. Currently, my research at UC Berkeley focuses on evaluating avian blood glucose regulation and its physiological consequences for flight performance and migratory behavior. When I am not doing science, I enjoy listening to music, going hiking and birdwatching, and rearing my own brood.
Giovanna Selleghin Veiga
Visiting Scholar, Nery Lab
I’m a PhD student from Brazil interested in studying comparative evolutionary genomics of marine mammals. I did my BS at the University of Campinas (UNICAMP) where I’m also doing my PhD at the Laboratory of Evolutionary Genomics under the supervision of Dr. Mariana Nery. The main focus of my work is to use bioinformatics and genomes to understand the evolution of antioxidant enzymes. Recently, I am currently a Visiting Scholar at the Vázquez-Medina lab where I am comparing the gene expression signatures of whale and seal primary cells under hypoxia and reoxygenation, trying to understand how these different mammalian groups respond to low oxygen tensions.
Alumni
Kaitlin Allen (PhD 2024)
Berkeley Fellow
NSF GRFP Fellow
Kaitlin studied oxidative stress and ischemia/reperfusion tolerance mechanisms in diving mammals. Kaitlin won a postdoctoral fellowship and is now a postdoctoral researcher at Woods Hole Oceanographic Institution.
José Arevalo (PhD 2024)
American Physiological Society Porter Physiology Fellow
Jose studied physiological mechanisms underlying metabolic inflexibility in aging and the role of Prdx6 in supporting mitochondrial function in skeletal muscle. José is now a postdoctoral fellow at the Buck Institute for Research on Aging.
Emily Lam (PhD 2025)
DOD NDSEG Fellow
Philomathia Graduate Student Fellow
Emily studied the effects of anthropogenic stress on marine mammals at the cellular and organismal levels. She is now a postdoc at UCSF.
Julia María Torres Velarde
Former UC MEXUS Postdoctoral Fellow
Julia studied how elephant seals can tolerate very high glucocorticoid levels and the cytoprotective effects of the antioxidant enzyme Prdx6 in the lung endothelium. Julia is now a researcher at CIAD in Mazatlan, Mexico.
Andrea Salvador Pascual
Former Postdoctoral Researcher
Andrea studied metabolic inflexibility in aging and contributed to our work on Prdx6 in the pulmonary endothelium.
David Ensminger
Former NSF PRB Fellow
David studied the impact of glucocorticoids on oxidative stress, inflammation, and immune function in elephant seals. David is now an Assistant Professor in the Department of Biological Sciences at San Jose State University.
Federico Kong-Gonzalez
Undergraduate researcher
Fede studied the physiological mechanisms of how air-breathing animals are able to dive for prolonged periods of time.
Eqlima Tahiry
IB SURE scholar
Eqlima studied how sea turtle cells manage oxidant stress during her summer-long research experience.
Heidi Avalos
Undergraduate researcher
Heidi graduated in Molecular and Cell Biology, with an emphasis in Cell Biology, Development, and Physiology. She worked with José Arevalo investigating mitochondrial function and lipid peroxidation in skeletal muscle cells.
Sarah Villa
Undergraduate researcher
Sarah majored in molecular and cell biology and minored in nutritional science. She was working with Manny to understand the metabolic response in bats when subjected to hypoxic and normoxic conditions.
Dua Shoaib
Undergraduate researcher
Dua is pursuing a major in Molecular and Cell Biology with a strong emphasis on neurobiology at UC Berkeley. She worked at the Vazquez-Medina Lab alongside Gaby where we investigated and compared the physiological adaptations of sea turtles and lizards.
Eva Utke
Undergraduate researcher
Eva studied the formation of skeletal muscle tissue and proteins that drive myogenesis.
Diana Sam
Undergraduate researcher
Diana studied microbats' cancer risk and somatic mutation rate and the relationship between species’ life expectancy and cancer risk.
Stella Recht
Undergraduate researcher
Stella worked on thermal imaging analysis to explore the relationship between habitat degradation and thermoregulation in Northern elephant seals.
Maxine Mouly
Undergraduate researcher, ESPM Honors Thesis
Maxine assessed the effects of warming on the thermoregulatory capacity of elephant seals and their potential for behavioral adjustments. Maxine is currently a graduate student at the University of Amsterdam.
Queenie Li
Undergraduate researcher
Queenie studied mitochondrial dysfunction in Prdx6 knock-out mice under Jose Arevalo’s mentorship.
Yuka Takahashi
Undergraduate researcher
Yuka studied the thermoregulatory capacity of elephant seals in the field, as well as using cell culture lab techniques.
Ana Castello
Undergraduate researcher, MCB Honors Thesis
Anna graduated with a BS in Molecular Cellular Biology and minored in History. Anna analyzed thermal images of elephant seals to determine how thermoregulation and thermal stress change with warming temperatures.
Kyra Henderson
Undergraduate researcher
Kyra studied Molecular and Cellular Biology, with an emphasis on Neurobiology. Kyra conducted cell research on elephant seals, California sea lions, and sea turtles.
Marvin Miller
Undergraduate researcher
Marvin researched the effect of aging on the lactate receptor GPR81 and metabolic inflexibility.
Alexander Li
Undergraduate researcher, MCB Honors thesis
Alex studied how endothelial cells derived from seals adapt to hypoxia and oxidative stress. Alex is a Senior Research Associate at Calico.
Lauren Zane
Undergraduate researcher, IB Honors Thesis
Lauren studied the relationship between glucocorticoids and telomeres across non-primate vertebrates and received the Departmental Natural History award for her work. She is now a PhD student at the University of Rhode Island.
Diamond Luong
Undergraduate researcher, IB Honors Thesis
Diamond studied the role of peroxiredoxin 6 (Prdx6) in the response to lipid peroxidation in seal and human placenta cells. Diamond first worked as a Research Coordinator at UCSF is now a Medical Student at UC San Diego.
Emily Gibson
Undergraduate researcher, MCB Honors thesis
Emily studied DNA methylation and gene expression in response to fasting in elephant seals. Emily is currently a PhD student at Princeton.
Noemi Reyes
Undergraduate researcher
Noemi worked to develop a novel model system using primary cell cultures derived from marine mammals to study the effects of chronic stress on muscle atrophy. Noemi is currently a Project Coordinator at LGC Biosearch Technologies.
Esmeralda Garcia-Orosco
Undergraduate researcher
Esmeralda studied oxidative stress and ischemic tolerance in seal and human cells. Esme went to grad school at Thomas Jefferson University and is currently a Scientist at Avid Bioservices.